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KMID : 0371620090240010037
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Journal of Wonkwang Medical Science
2009 Volume.24 No. 1 p.37 ~ p.39
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Periodic Alternating Gaze Deviation and Periodic Alternating Nystagmus in Alcoholic Extrapontine Myelinolysis
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Kang Sung-Won
Lee Myoung-Jea
Jeong Ju-Lie
Kim Young-Jin
Yang Hyun-Duk
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Abstract
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Background: Periodic alternating gaze deviation(PAGD) and periodic alternating nystagmus(PAN) are rare forms of abnormal eye movement. Multiple lesions in the cerebellum and brainstem have been reported with PAN and PAGD.
Case Report: A 50-year-old man presented with severe vomiting after binge drinking. The next morning he. became vegetative state and showed PAGD and PAN. Brain MRI showed findings compatible with extrapontine myelinolysis(EPM) without any brainstem or cerebellar lesions.
Conclusions: We postulate that the disturbed GABAnernic system in the pathway from the cerebellum to vestibular nuclei caused probably by EPM developed PAGD and PAN.
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KEYWORD
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deviation, nystagmus, myelinolysis
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